Cannabinoid Dictionary

Cannabinoids are molecules found in many living things, such as cannabis, and humans. Yes, that means you! Phytocannabinoids are found in plants (phyto means of a plant). Endocannabinoids are found in humans (endo means within). Endocannabinoids interact with a unique biological system in our bodies called the Endocannabinoid System (ECS).

Scientists have discovered over 100 cannabinoids within the cannabis plant. CBGA and CBGV are the precursors or parent cannabinoids to all other cannabinoids. Through a process called decarboxylation, these molecules convert from one cannabinoid to another when heated/exposed to light.

The Endocannabinoid System is known to regulate many essential functions that help maintain homeostasis within the body. Homeostasis is the body’s state of balance. These functions include regulating sleep, mood, appetite, nausea, pain, memory, and reproduction.

The ECS is made up of enzymes, cannabinoids, and receptors; CB1 receptors that are primarily found in the central nervous system, and CB2 receptors found in tissues throughout the immune system. Phytocannabinoids act as a supplement to our body’s own endocannabinoids, similar to taking a protein supplement before the gym.

There are many different cannabinoids with different medicinal benefits. The most popular are THC and CBD, but as research progresses, benefits of other cannabinoids are gaining popularity. Cannabinoids seem to be the most beneficial and enhance each other’s medicinal effects when they are able to work together in whole plant cannabis products. This idea is known as The Entourage Effect: cannabinoids, terpenes, and flavonoids working synergistically to produce the best overall medicinal effect. Understanding what each cannabinoid does will make it easier to find the ideal product to treat your condition.

Common Cannabinoids and Their Benefits

CBGA: Cannabigerolic Acid

Precursor to THCA, CBCA, CBDA, and CBG (which further convert into THC, CBD, CBC, and CBN, etc.)

Anti-inflammatory and analgesic effects

CBGVA: Cannabigerovarinic Acid

Precursor to THCVA, CBDVA, CBCVA, and also CBG

Anti-inflammatory 

CBG: Cannabigerol

Non-intoxicating

Anti-inflammatory, anti-tumor, anti-bacterial, and possible neuroprotectant.

Known to be effective in treating:

    • Huntington’s Disease
    • IBS and IBD
    • Cancer
    • Chronic Pain
    • Insomnia
    • Glaucoma
    • Psoriasis
    • Pain 
  • THC: Tetrahydocannabinol
    • Responsible for the psychotropic effects a.k.a the “high” associated with cannabis
    • Anti-inflammitory, anti-convulsant, anti-emetic, neuro-protectant, appetite stimulant

Known to be effective in treating:

    • Pain
    • PTSD
    • Insomnia
    • Nausea
    • Appetite loss
    • Anorexia
    • HIV
    • Seizures
    • Neurological Conditions
    • Anxiety (THC seems to decrease anxiety in low doses, but may increase it in high doses) 
  • THCV: Tetrahydrocannabivarin
    • Similar to THC, THCV can have a euphoric effect in high doses
    • Appetite suppressant, anti-inflammatory, encourages bone growth, said to help regulate blood sugar, possible anti-cancer effects

Known to be effective in treating:

    • Diabetes 
    • PTSD
    • Panic Attacks
    • Tremors
    • Muscle Spasms
    • Osteoporosis
    • Prostate Cancer 
  • THCVA: Tetrahydrocanabivarinic Acid
    • Precursor to THCV, THCVA turns to THCV through decarboxylation
    • Medicinal benefits are known to be similar to THCV
  • THCA: Δ9-Tetrahydrocannabinolic Acid
    • THCA is essentially THC in it’s raw form, before it is “activated.” THCA itself is non-intoxicating. It is essentially a THC molecule with a layer of acid around it, and once it is heated, THCA turns to THC through a process called decarboxylation.
    • Expect to receive the same medicinal effects of THC after heating THCA.
    • Raw THCA is known to have powerful anti-inflammatory properties, some patients have “juiced” raw cannabis in order to experience the effects of THCA. This method is usually used to treat gastrointestinal issues.

Known to be effective in treating:

    • Raw THCA is known to have powerful anti-inflammatory properties, some patients have “juiced” raw cannabis in order to experience the effects of THCA. This method is usually used to treat gastrointestinal issues.
  • Δ8THC (Delta-8): Δ8-Tetrahydrocannabinol
    • Similar to THC and THCV, but delivers a slightly less potent psychotropic effect
    • The National Cancer Institute states Δ8THC has antiemetic (anti-nausea), anxiolytic (anti-anxiety), appetite-stimulating, analgesic, and neuroprotective properties.

Known to be effective in treating:

    • Anxiety
    • Pain
    • Alzheimer’s / Dementia
    • Anxiety Disorders
    • Cancer / Chemotherapy
    • Nausea and Vomiting
    • Cachexia
    • Depression
    • Inflammatory Brain Conditions (Neuro-protective)
    • Loss of Appetite
  • CBD: Cannabinol
    •  A non-intoxicating cannabinoid, naturally produced in high amounts in hemp and low amounts in marijuana
    • Powerful anti-inflammatory, antioxidant, anti-proliferative, anti-angiogenic and pro-apoptotic. 

Known to be effective in treating:

    • Autism
    • Anxiety and PTSD
    • Epilepsy (seizures)
    • Pain
    • Mood Disorders
    • Parkinson’s Disease
    • HIV
    • Insomnia
    • Multiple Sclerosis
    • Chron’s Disease and IBS
    • Cancer
  • CBDA: Cannabidiolic Acid
    • Non-intoxicating
    • Precursor to CBD
  • CBDV: Cannabidivarin
    • Non-intoxicating
    • Antioxidant, anti-epileptic, anti-nausea, and anti-inflammatory. Also said to help improve memory.

Known to be effective in treating:

    • Seizures
    • Nausea and Vomiting
    • HIV
    • Muscular Dystrophy
    • Rett Syndrome
  • CBDVA: Cannabidivarinic Acid
    • Precursor to CBDV
  • CBC: Cannabichromene
    • Non-intoxicating 
    • CBC has a unique relationship with pain receptors in the brain, making it an excellent pain treatment
    • Anti-bacterial, anti-fungal, and said to decrease neurogenic inflammation and encourage the natural production of our bodies’ own Endocannabinoids.

Known to be effective in treating:

    • Fibromyalgia
    • Multiple Sclerosis (MS)
    • Neurodegenerative Conditions
    • Alzheimer’s
    • Digestive/Gastrointestinal Disorders  
  • CBCVA: Cannabichromevarinic Acid
    • A Precursor to CBC
    • Similar benefits to CBC, known to have and antibacterial properties
  • CBCA: Cannabichromenic Acid
    • Another Precursor to CBC, similar effects
    • Known to have anti-inflammatory, anti-anxiety and anti-fungal effects

Known to be effective in treating:

    • Anxiety and Depression
    • Arthritis
    • Athlete’s Foot
    • Cancer
    • Candidiasis
  • CBN: Cannabinol
    • Non-intoxicating
    • Popular for it’s highly sedative effects, has also shown promise as a neuroprotectant, anti-inflammatory, anti-bacterial, anti-convulsant, appetite stimulant and analgesic.
    • Steephill, reported “2.5mg to 5mg of CBN has the same level of sedation as a mild pharmaceutical sedative, with a relaxed body sensation similar to 5mg to 10mg of diazepam.”

Known to be effective in treating:

    • Insomnia
    • Rheumatoid arthritis
    • Crohn’s Disease
    • Seizures 
    • Chronic Pain

Cannabis is a complex plant with many medicinal properties. As cannabis becomes more widely accepted as medicine, more research will be available to understand the full potential of this incredible plant. After reading this, hopefully you have an easier time finding the ideal cannabis products to treat your symptoms. If you have any questions, please message us or email us at info@pammj.com.

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